About

WHO WE ARE
The SESCRN are a highly trained and motivated work force, consisting of medical, nursing, radiography, bio-chemistry, pharmacy, data management and administrative professionals working in each of the hospitals across the South East of Scotland. Each member of the team is vital to the process of delivering the most up to date clinical studies to our patients throughout the South East region.

ABOUT US
The South East Scottish Cancer Research Network (SESCRN) recruits patients who are from NHS Lothian, NHS Fife, NHS Borders and NHS Dumfries and Galloway Health Boards, and SESCRN supports cancer research in all these regions.

Our aim is to empower cancer patients in Scotland by providing the best clinical opportunities for them whilst enabling access to clear information, and clinical research support regarding research studies across a range of disease sites whilst integrating this into local cancer care. Our network of dedicated health professionals will support patients and their families to understand clinical research and the potential impact their role has within it.

The SESCRN brings together many partners involved in research such as:

The Medical Research Council Institute of Genetics and Molecular Medicine (IGMM)
The University of Edinburgh (U of E)
Medical Research Council Human Genetics Unit (MRC HGU)
Edinburgh Cancer Research Centre (ECRC)
Experimental Cancer Medicine Centre (ECMC)
Cancer Research UK (CRUK)

The Medical Research Council Institute of Genetics and Molecular Medicine (IGMM) within The University of Edinburgh (U of E) constitutes one of the largest aggregates of human molecular genetics research capacity in the UK, and brings together over 500 research and support scientists in a single, scientific endeavour. This includes the Medical Research Council Human Genetics Unit (MRC HGU), Edinburgh Cancer Research Centre (ECRC), Experimental Cancer Medicine Centre (ECMC) and Cancer Research U.K. (CRUK). Working in partnership with these organisations allows us to provide a research service across the board, beginning with the bench work in the laboratory to the patients bed side, delivering the latest treatments in which all staff work to the same exacting procedures and standards, providing a world class service for our patients.

WHAT WE DO
In collaboration with our partner organisations we are involved in a wide variety of cancer research. The aim of our research is to help us understand cancer better and to help our patients effected by the disease.

The research we undertake is done in many different forms, for example:

Bench Work: The Medical Research Council Institute of Genetics and Molecular Medicine (IGMM) at The University of Edinburgh forms one of the largest and comprehensive, human molecular genetics research capacity in the UK, and brings together over 500 research and support scientists in a single, scientific endeavour. These scientists work tirelessly to find new treatments in the fight against cancer by looking at genetic patterns, drug development and DNA profiling.

Translation Research: This specific type of research looks at patients biological tissue and blood samples to improve our understanding of cancer, how it develops and responds to treatments. This can include looking at genes which may cause cancers, factors that can predict how patients may respond to treatments as well as a variety of other research.

Clinical Studies: These studies help us to evaluate treatments such as new drugs or radiotherapy regimens to ensure they are safe and that they improve outcomes for patients. New drugs go through strict testing in the laboratory before they are offered to patients. After the laboratory testing there are 3 main phases of clinical studies. Each phase has a different purpose:

Phase 1 studies involve small numbers of patients and aim to establish a safe dose for the drug and identify any possible side effects.
Phase 2 studies involve larger numbers of patients and look at different ways of delivering the treatment, whether the new delivery proves effective and what dose and frequency to use.
Phase 3 studies involve large numbers of patients. These studies compare new treatment against the best available current treatment to see which is most effective against cancer.

Other Studies: Other clinical studies (such as questionnaires) may look at new ways of preventing, diagnosing and screening cancer or cancer related side effects such as pain or fatigue.

MORE INFORMATION
Please see the studies page for information on clinical trials currently recruiting in this region. Our links page has some additional information about other research organisations that you may find useful.